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Restaurants near The Inn at Mayo Clinic

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126 restaurants available nearby

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A photo of M Brothers at Mayo restaurant
1. M Brothers at Mayo
4.9
Exceptional(651)
££££
• Seafood • Jacksonville
Booked 4 times today
M Brothers at Mayo is a hidden gem tucked inside Jacksonville’s Mayo Clinic—a delightful reprieve where culinary excellence meets refined hospitality. A Medure Brothers Culinary Concept by acclaimed chefs Matthew and David Medure, M Brothers is led by Executive Chef Thomas Rivers and offers a sophisticated dining experience on Mayo Clinic's campus.Enjoy globally inspired cuisine crafted with seasonal ingredients, and don’t miss our monthly Culinary Passport tasting menus, where we explore flavors from a different region of the world each month.Visit our lounge for a handcrafted cocktail or select a bottle from our extensive wine list. Join us for Lunch Monday–Friday and Dinner Monday–Saturday. Unwind during Happy Hour in the lounge, Monday–Friday from 4–6 PM. Whether you're sampling guest favorites like our burrata appetizer, savory shrimp étouffée, or a seasonal chef-driven entrée, M Brothers is a destination worth discovering.
A photo of Eleven South Bistro restaurant
2. Eleven South Bistro
4.8
Exceptional(4604)
££££
• Contemporary American • Jacksonville Beach
Booked 23 times today
At Eleven South, our food philosophy is simple – a taste for every palate and a palette for every season. Our menu is the centerpiece of the dining experience and features an exclusive variety of seafood, steaks, fresh fish and pasta dishes. Our open flame mesquite wood grill is our distinction and adds delectable flavor to many of our signature dishes from our signature Sea Bass to our steaks and appetizers.
A photo of O-Ku - Jacksonville Beach restaurant
3. O-Ku - Jacksonville Beach
4.8
Exceptional(990)
££££
• Japanese • Jacksonville Beach
Booked 53 times today
O-Ku provides a fresh and innovative take on traditional Japanese sushi and cuisine. O-Ku's menu is comprised of signature starters, contemporary Japanese entrees and seasonal traditional sushi that reflect the uniquely designed space. The beachside location with waterfront and rooftop dining offers traditional sashimi and specialty rolls, sourcing seafood from the finest fish markets in Tokyo and Hawaii alongside local and seasonal ingredients.
A photo of Mezza Luna restaurant
4. Mezza Luna
4.8
Exceptional(2240)
££££
• Italian • Neptune Beach
Booked 43 times today
Locally owned and operated, we offer 3 different seating options:Standard seating: our formal dining room, perfect for date night, business dinners, gatherings with friends and family.Bar seating: tables in our lounge, family friendly, live music 6-9pm Sunday-Thursday.Outdoor Seating: covered patio, with fans in the summer and enclosed with heat in the winter. Family friendly and excellent for larger parties.In the interest of prompt and superior service, we do not split checks by item. Checks may only be split evenly. We encourage the use of Venmo. Reservations are recommended.
A photo of Refinery Jax Beach restaurant
5. Refinery Jax Beach
4.3
Awesome(1027)
££££
• American • Jacksonville Beach
Booked 20 times today
Welcome to Refinery Jax Beach, one of Jacksonville Beach's premier oceanfront dining destinations. Recognized by USA Today as one of the Top 15 Waterfront Restaurants in Florida, Refinery combines breathtaking Atlantic Ocean views, scratch-made cuisine, and handcrafted craft cocktails to create an unforgettable dining experience.Choose from multiple spaces—Refined Dining, Lounge, and Ocean Bar—each offering its own atmosphere, from romantic date nights and celebratory dinners to casual gatherings and vibrant evenings with live entertainment.Our chefs prepare every dish using fresh, high-quality ingredients, featuring fresh seafood, premium steaks and variety of chef-inspired entrées. Pair your meal with a signature cocktail, while enjoying some of the best waterfront views in Jacksonville Beach.Whether you're joining us for brunch, lunch, dinner, happy hour, or a special occasion, Refinery delivers exceptional food, genuine hospitality, and an unforgettable oceanfront experience.
A photo of Dwight's Bistro restaurant
6. Dwight's Bistro
5.0
Exceptional(1579)
££££
• French • Neptune Beach
Booked 8 times today
Dwight's Bistro, located in Jacksonville, Florida, features a unique blend of dishes from across Europe. The restaurant has private party rooms available for 12 or 20 people. Dwight's Bistro features a wine list that is available by the glass or by the bottle. The starters on the menu offered at Dwight's Bistro includes a chef's cheese plate, pan cooked foie gras and escargot. Chopped salad, Caesar salad and palm salad are offered as well. Entres are served with a vegetable and ravioli and feature veal piccata, filet mignon and crab cakes. Handmade pasta choices consist of fettuccini carbonara, veal sausage spaghetti, ravioli of the day and angel hair puttanesca.
A photo of Oaxaca Club restaurant
7. Oaxaca Club
4.5
Awesome(562)
££££
• Mexican • Jacksonville Beach
Booked 15 times today
Contemporary Mexican Cuisine in a modern setting. Curated Mezcal and Tequila menus to match authentic Oaxacan and regional Mexican food.At Oaxaca Club, each dish tells a story of ancient recipes and cooking techniques passed down through generations. From our traditional hand-made piquín, verde, and chipotle salsas, to our delicate Aguachile Amarillo with fresh serranos and quelites, to our hearty bone-in braised short-rib birria, we see it as our mission to capture the essence of Oaxaca's endless love affair with food, and bring a little piece of Oaxaca to you.Similar to wine, Mezcal reflects where it's grown; in Oaxaca's sun-soaked hills and rugged valleys, ancient agave plants absorb the region's rich volcanic soils, imbuing the spirit with a subtle earthiness. Our carefully curated menu is always evolving with the seasons, ensuring each visit brings the freshest and most vibrant flavors to your table and to those you share it with.
A photo of Argyle restaurant
8. Argyle
4.6
Exceptional(345)
££££
• Contemporary American • Ponte Vedra Beach
Booked 7 times today
Argyle is Ponte Vedra Beach’s award winning chef driven dining destination, where thoughtful sourcing, scratch made execution, and seasonal Contemporary American cuisine come together in a polished yet approachable setting. Led by Chef Blackford, recognized for his passion for technique, creativity, and elevating familiar flavors, each menu reflects an uncompromising commitment to quality. From house made breads, pastas, dressings, and desserts to signature dishes that blend refinement with comfort, Argyle offers an experience that feels both memorable and effortless. With elevated hospitality, seasonal evolution, and a setting designed to feel stylish yet welcoming, Argyle is helping redefine what dining in North Florida can be.
A photo of Bubba Gump - Jacksonville restaurant
9. Bubba Gump - Jacksonville
4.1
Excellent(42)
££££
• Seafood • Jacksonville Beach
Booked 21 times today
Capturing the magic that made "Forrest Gump" an American classic, Bubba Gump Shrimp Co. serves scratch-made, southern-style comfort dishes plucked straight off the silver screen – we’re talking sautéed shrimp, fried shrimp, coconut shrimp, shrimp scampi...(shall we go on?), alongside award-winning baby back ribs, burgers, salads and more in a fun and energetic atmosphere.
A photo of Coop 303 restaurant
10. Coop 303
4.3
Awesome(1278)
££££
• American • Atlantic Beach
Booked 12 times today
Coop 303 was born from a desire to prepare and serve delicious, and modern food paired with unique cocktails with genuine, caring hospitality — food and service from the heart.Coop 303 features curated dishes with a modern flavor and a classic feel. Two floors of dining and sipping with two unique rooms plus relaxing outdoor patios. Join us at our full-service downstairs bar where we showcase our classic and specialty cocktails, a variety of wines and an extensive whiskey collection.Coop 303 has a one-of-a-kind space on the top floor known as The Living Room Lounge which brings sexy sophisticated vibes of specialty cocktails and a live DJ to Atlantic Beach. Join us for dinner and work your way upstairs to enjoy all the experiences in one place.

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Dining near The Inn at Mayo Clinic at a glance

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Most popular restaurant

popular restaurant

Eleven South Bistro

4.8

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Exceptional reviews

Most popular cuisine

popular cuisine

Contemporary American

Average check amount

£25 and under

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Discover best restaurants near The Inn at Mayo Clinic

Experience comfort and convenience at The Inn at Mayo Clinic, a top choice for visitors to the Mayo Clinic in Jacksonville, Florida. Where to Eat Near The Inn at Mayo Clinic? The dining scene near The Inn is vibrant and diverse, offering something for every palate. Explore options ranging from sophisticated seafood dining with fresh catches to delightful French bistros that serve up classic dishes and exceptional wines. You can also enjoy Italian fare featuring handmade pastas, along with lively spots that offer a casual atmosphere perfect for gathering with friends or family. Whether you're savoring a delectable brunch or enjoying a romantic dinner, the nearby restaurants provide memorable culinary experiences that will complement your stay. Discover a culinary adventure just steps away from The Inn at Mayo Clinic.

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